On October 24, 2024, our College of Biomedical Engineering & Instrument Science (CBEIS) successfully hosted the 15th “Lv Weixue Academic Forum” in conjunction with the symposium on Mechano-Biological Coupling in Liver Regeneration and Reconstruction at Zhou Yiqing Suite, Yuquan Campus, Zhejiang University.
The forum featured a keynote address by Researcher Mian Long, a distinguished scholar from the Institute of Mechanics, Chinese Academy of Sciences (CAS). Dr. Long has served as the director of CAS National Microgravity Laboratory and Beijing Key Laboratory of Tissue Engineering Construction and Mechanobiology. He is also a recipient of the CAS Hundred Talents Program, a chief scientist of the National Basic Research Program of China (973 Program), an executive committee member of the World Council of Biomechanics, vice president of the Chinese Society of Theoretical and Applied Mechanics, and a fellow of the American Institute for Medical and Biological Engineering.
The lecture, chaired by Professor Liang’fei Tian, a researcher under Zhejiang University’s Hundred Talents Program, focused on the mechanical microenvironment of liver physiology and its pathological changes, exploring how specific mechanical factors such as fluid shear stress, mechanical stretching, and matrix stiffness influence hepatocyte proliferation and sinusoidal endothelial cell dedifferentiation. Dr. Long aimed to provide a scientific foundation for understanding the initiation of hepatocyte proliferation, regulating liver regeneration and reconstruction, and promoting drug screening for liver diseases.
The whole lecture was lively, with active participation from faculty and students who engaged in deep discussions. Dr. Long also presented his teams' works on mechanical models and provided practical application examples, which arose significant interest and discussion among attendees. He patiently answered questions and shared insights into his academic journey and future research prospects.
This event not only enriched the audience's understanding of mechano-biological coupling in liver studies but also fostered a vibrant exchange of ideas between students and experts in the field.
